%0 Journal Article %@nexthigherunit 8JMKD3MGPCW/46JKC45 %@holdercode {isadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S} %@resumeid %@resumeid %@resumeid 8JMKD3MGP5W/3C9JHR6 %@archivingpolicy denypublisher denyfinaldraft24 %@usergroup administrator %@usergroup estagiario %3 Bourotte_association.pdf %X Air pollutants are associated with adverse respiratory effects mainly in susceptible groups. This study was designed to assess the impact of the ionic composition of particulate matter on asthmatic respiratory functions in Sao Paulo city. From May to July 2002, fine and coarse particulate matter fractions were collected and their respective chemical composition with respect to major ions (Na+, Mg2+, K+, Ca2+, NH4+, Cl-, NO3- and SO42-) were determined in each aqueous-extract of fraction. The results showed predominant concentrations SO42- (48.4%), NO3- (19.6%) and NH4+ (12.5%) in the fine fraction, whereas NO3- (35.3%), SO42- (29.1%), Ca2+ (13.1%) and Cl- (12.5%) were the predominant species in the coarse 3 4 fraction. The association between the chemical components of both fractions and the daily peak expiratory flow (PEF) measurements (morning and evening) of the 33 asthmatic individuals were assessed through a linear mixed-effects model. The results showed a significant negative correlation (decrease of PEF) between morning PEF and coarse chloride (3-day moving average) and between evening PEF and coarse Na+ (3-day moving average), coarse Mg2+ (3-day moving average) and coarse NH4+ (2- and 3-day moving average). A significant negative correlation has also been observed between morning and evening PEF and Mg2+ in the fine fraction. These results suggest that some particle chemical constituents may increase the responsiveness of airways and that coarse particles that deposit in the upper airways may be more relevant for asthmatic response and irritation. However, the results do not prove a clear causal relationship. %8 MAR %N 10 %@secondarydate 20070601 %T Association between ionic composition of fine and coarse aerosol soluble fraction and peak expiratory flow of asthmatic patients in Sao Paulo city (Brazil) %@secondarytype PRE PI %K PM2.5, PM2.5-10, aerosol composition, major ions, aqueous extracts, PEF, urban pollution. %@visibility shown %@group %@group %@group DMA-INPE-MCT-BR %@secondarykey INPE-14730-PRE/9701 %@copyholder SID/SCD %@issn 1352-2310 %2 sid.inpe.br/mtc-m17@80/2007/06.01.13.57.26 %@affiliation Universidade de Saõ Paulo (USP), NUPEGEL %@affiliation Universidade de Saõ Paulo (USP), NUPEGEL %@affiliation Instituto Nacional de Pesquisas Espaciais (INPE) %@affiliation Núcleo de Estudos em Epidemiologia Ambiental, USP %@affiliation Núcleo de Estudos em Epidemiologia Ambiental, USP %@affiliation Universidade de São Paulo (USP) %B Atmospheric Environment %P 2036-2048 %4 sid.inpe.br/mtc-m17@80/2007/06.01.13.57 %D 2007 %V 41 %A Bourotte, Christine, %A Curl-Amarante, Ana Paula, %A Forti, Maria Cristina, %A Pereira, Luiz A. A, %A Braga, Alfesio L, %A Lotufo, Paulo A, %@dissemination WEBSCI; PORTALCAPES. %@area MET